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The Cleanroom is a multiblock that provides a sterile environment inside it. More specifically, when running at 100% efficiency, it satisfies the "Needs Cleanroom" requirement for any machine that runs inside it. A Cleanroom at less than a 100% efficiency rating has a chance of voiding items equal to the difference between its current rating and one hundred. Potential loss only applies to recipes that require the Cleanroom.

How to Build

A cleanroom is a hollow, variable-sized structure between 3x4x3 and 15x15x15 (width x height x depth). Its footprint (width x depth) must be an odd numbered square; 3x3, 5x5, 7x7, etc. There are no restrictions on the height other than a minimum of four and a maximum of fifteen blocks. The Energy Hatch only powers the cleanroom itself; Machine Hulls are used to supply power to machines inside.

Requires:

x1 Cleanroom Controller; top-most layer, perfectly centered
x0-168 Filter Machine Casings; entire top layer except controller and edges
x1 Maintenance Hatch; anywhere that is not an edge
x1 Energy hatch; anywhere that is not an edge
Up to 1 Reinforced Door^[1]
Up to 1 Elevator block, in the floor^[2].
Up to 1 Travel Anchor, in the floor^[2].
Up to 10 Machine Hulls; anywhere that is not an edge. This can power the machines inside a cleanroom.
Plascrete Blocks everywhere else (up to five percent of these can be replaced with reinforced glass - note that it is very hard to move reinforced glass without breaking it)

Caution:

It seems that the door and optional elevator block/anchor count against the 5% not plascrete calculation, so reducing the amount of Reinforced Glass may be necessary to get the Cleanroom to form.

↑ Despite the tooltip making the Reinforced Door sound mandatory, it is indeed optional.
↑ ^2.0 ^2.1 Any number of Elevators/Anchors can be placed inside the cleanroom instead of as part of the structure.

Usage

Doing a "Needs Cleanroom" recipe in a cleanroom without 100% efficiency can potentially void items. The current efficiency is displayed via Waila when looking at the controller. Be absolutely sure that your cleanroom is running at 100% efficiency during use, either with a Extra Utilities Portable Scanner or a GregTech Sensor Kit on an Industrial Information Panel. (Right click the Controller to bind the Sensor Kit to the controller.) Furthermore, for each maintenance issue it currently has, the cleanroom will have a 10% chance of voiding items for machines running a "Needs Cleanroom" recipe.

When at 100% efficiency, the cleanroom drains 4 EU/t. However, while it's charging up to that value (0% through 99%), the cleanroom will drain 40 EU/t. For this reason, it is recommended to have at least two amps of LV feeding into an LV energy hatch (or 1 amp of anything higher than LV feeding into an appropriate energy hatch). Providing a higher tier Energy Hatch will overclock the cleanroom, making it gain efficiency faster at the cost of higher power use, even after 100% is achieved.

Accessing the Cleanroom

A Reinforced Door, Travel Anchor, and/or Elevator can all be used to enter and exit the cleanroom. The door requires a redstone signal to open and must be closed for 100% efficiency. Anchors and Elevators do not reduce a cleanroom's efficiency when used. The second Elevator block can be placed on top or below, while another Travel Anchor can be anywhere in its range.

Machine Hulls

Machine hulls allow players to transfer items, fluids, and energy in and out of the cleanroom. Putting ingredients into a hull is easy enough. Treat it basically like any other inventory/tank when transferring items/fluids and like a machine face when transferring power, since it can accept GT cables.

On the other side of the hull, right-clicking with a Wrench will control where the "dot" face points and this face will be where ingredients come out. Note that the hull does not auto output items and fluids. There will need to be something pulling items and/or fluids out of the hull on the other side. Attaching a Conveyor and Pump Covers on a hull does not work because it itself holds no EU (it merely transports it) to power the covers. However, attaching Fluid Pipes with covers attached to them (screwdriver set to "import") will work. The same goes for covers attached to machine faces (screwdriver set to "import") facing the machine hull dot face.

EU is transferred directly to the cable or machine face the dot face is pointing at and does not need anything special "pulling" the EU out. A hull can only transfer as much energy as the tier of the hull. For example, an HV Machine Hull can only output one Amp of HV.

Because there are a max of ten machine hulls per multiblock, it is important to be efficient with hulls. A single dedicated output hull from inside the cleanroom to the outside is highly recommended, rather than having an output hull for each machine inside. A dedicated power line is recommended as well.

Sample Minimum Build

The following is a sample Cleanroom build of minimal size (26 Plascrete, no Filter Casings) with automation to get you started with HV Circuits. Note that this setup requires using the Reinforced Door to swap out the lens - close the door promptly to preserve efficiency.

Top Layer:
- 1 Cleanroom Controller: top layer, center
- +8 Plascrete Blocks: top layer, edges
Middle Top:
- 1 MV Energy Hatch, rear middle
- 1 MV Machine Hull, middle left (Item Input)
  - 1 Hopper, outside, pointing into Machine Hull
- 1 Brass Pipe, inside center
  - 1 MV Conveyor Module, pointed left on Brass Pipe, set to Import (Screwdriver x1)
  - 1 Wooden Cover, pointed up on Brass Pipe (blocking the Cleanroom Controller)
- 1 Chest (or other container), outside middle right
- 0 Reinforced Door (top half)
  - 1 Lever, outside front right
- +5 Plascrete Blocks: remainder
Middle Bottom:
- 1 MV Machine Hull, rear middle (Power Input)
- 1 MV Advanced Precision Laser Engraver, inside center, set to Auto-Output Items
- 1 MV Machine Hull, middle right (Item Output)
  - 1 Brass Pipe, outside middle right
  - 1 MV Conveyor Module, pointed left on Brass Pipe, set to Import (Screwdriver x1)
    (Note: this pipe should connect to the Chest on the Middle Top layer.)
- 1 Maintenance Hatch, front left
- 1 Reinforced Door (bottom half)
- +4 Plascrete Blocks: remainder
Bottom Layer:
- +9 Plascrete Blocks

Elsewhere:
- 1 Industrial Information Panel
- 1 Industrial Information Panel Extender
- 1 Lever, behind Information Panel, on
- 1 GregTech Sensor Kit
 - Settings: #3 Off

This setup can be upgraded - take a look at the Tips section below!

Tips

Do not forget about upgrading hulls when upgrading a cleanroom to handle higher tier voltage machines. Overvolting will result in disaster.
A "Needs Maintenance" cover will also come in handy for alerting players about maintenance issues. Since the Cleanroom runs constantly while powered, it generates maintenance issues more frequently than intermittent machines.
Zinc is a relatively rare resource early on in the game. Because of this, it is recommended to expand a cleanroom vertically before expanding horizontally. This allows the player to focus on building plascrete blocks instead, which is much easier to make.
It is highly recommended to use Ender IO item conduits and fluid conduits to transfer items/fluids. Since different types of conduits are allowed to be placed in the same block, this greatly simplifies piping logic in and out of the cleanroom.
One can transfer multiple amps of energy into a cleanroom by up-transforming prior to sending energy into a hull and down-transforming inside the cleanroom. Be careful and remember that the correct voltage tier hull must be used when doing this.
You can use an elevator or other forms of teleportation to enter the cleanroom without opening the door.
Pollution does not affect cleanroom efficiency in any way, so it would also be possible to have combustion and gas generators running directly inside the cleanroom as a dedicated power source, so as not to deal with any wiring through hulls.
In order to get access to your ME Systeme inside of the cleanroom Wireless Connectors of AE2 Stuff can be used.

[1] Despite the tooltip making the Reinforced Door sound mandatory, it is indeed optional.

[teleport-2] 2.0 ^2.1 Any number of Elevators/Anchors can be placed inside the cleanroom instead of as part of the structure.

[1]

[2]

@@ Line 1: / Line 1: @@
+{{Infobox Test
-[[File:Cleanroom.png|thumb|right|alt=A white multiblock 5x5 cube with a small platform leading up to a dark grey door.  There are grills on the top, a single window, maintenence and energy hatches on the left side.|5x5 Cleanroom]]
+|name=Cleanroom
+|image=Cleanroom.png|alt=A white multiblock 5x5 cube with a small platform leading up to a dark grey door.  There are grills on the top, a single window, maintenence and energy hatches on the left side.
+|mod=Gregtech 5
+|type=Tile Entity
+|tooltip= Controller Block for the Cleanroom
+|quest=
+|tier=
+|machinesize=3x4x3 - 15x15x15
+|pollutionoutput=none
+|blastresistance=6-3000
+|hardness= 1-50
+|gteuusage=4-40 EU/t
+|gtvoltagein=
+|gtamperage=
+}}
 The Cleanroom is a multiblock that provides a sterile environment inside it. More specifically, when running at 100% efficiency, it satisfies the "Needs Cleanroom" requirement for any machine that runs inside it.  A Cleanroom at less than a 100% efficiency rating has a chance of voiding items equal to the difference between its current rating and one hundred.  Potential loss ''only'' applies to recipes that require the Cleanroom.
 == How to Build ==
-A cleanroom is a hollow, variable-sized structure. It is, at the very minimum, a 3x4x3 (WxHxD) structure and, at max, a 15x15x15 structure. The cleanroom's width and depth must be the same and odd. In other words, it should look like a square when looking down at it from above. It requires:
+A cleanroom is a hollow, variable-sized structure between 3x4x3 and 15x15x15 (width x height x depth).
+Its footprint (width x depth) ''must'' be an odd numbered square; 3x3, 5x5, 7x7, etc.  There are no restrictions on the height other than a minimum of four and a maximum of fifteen blocks.  The Energy Hatch only powers the cleanroom itself; Machine Hulls are used to supply power to machines inside.
+'''Requires:'''
-*1 Controller block; top-most layer, perfectly centered
+* x1 Cleanroom Controller; top-most layer, perfectly centered
-*Between 0 and 168 Filter Machine Casings; must fill all of the top layer except for the controller and the edges
+* x0-168 Filter Machine Casings; entire top layer except controller and edges
-*1 Maintenance Hatch; anywhere that is not an edge.
-*1 Energy hatch; anywhere that is not an edge. This powers the cleanroom only, not the machines inside.
+* x1 Maintenance Hatch; anywhere that is not an edge
+* x1 Energy hatch; anywhere that is not an edge
-*Up to 1 Reinforced Door; can be opened/closed with a redstone signal and must be closed for 100% efficiency<ref>Despite the tooltip making the Reinforced Door sound mandatory, it is indeed optional.</ref>
+*Up to 1 Reinforced Door<ref>Despite the tooltip making the Reinforced Door sound mandatory, it is indeed optional.</ref>
 *Up to 1 Elevator block, in the floor<ref name="teleport">Any number of Elevators/Anchors can be placed inside the cleanroom instead of as part of the structure.</ref>.
 *Up to 1 Travel Anchor, in the floor<ref name="teleport" />.
@@ Line 15: / Line 32: @@
 *Plascrete Blocks everywhere else (up to five percent of these can be replaced with reinforced glass - note that it is very hard to move reinforced glass without breaking it)
 {{Caution| It seems that the door and optional elevator block/anchor count against the 5% not plascrete calculation, so reducing the amount of Reinforced Glass may be necessary to get the Cleanroom to form.}}
 <references />
+== Usage ==
-Doing a "Needs Cleanroom" recipe in a cleanroom without 100% efficiency can potentially void items.  The current efficiency is displayed via WAILA when looking at the controller.  Be absolutely sure that your cleanroom is running at 100% efficiency during use, either with a Extra Utilities Portable Scanner or a GregTech Sensor Kit on an Industrial Information Panel. (Right click the Controller to bind the Sensor Kit to the controller.) Furthermore, for each maintenance issue it currently has, the cleanroom will have a 10% chance of voiding items for machines running a "Needs Cleanroom" recipe.
+Doing a "Needs Cleanroom" recipe in a cleanroom without 100% efficiency can potentially void items.  The current efficiency is displayed via [[Waila]] when looking at the controller.  Be absolutely sure that your cleanroom is running at 100% efficiency during use, either with a Extra Utilities Portable Scanner or a GregTech Sensor Kit on an Industrial Information Panel. (Right click the Controller to bind the Sensor Kit to the controller.) Furthermore, for each [[maintenance]] issue it currently has, the cleanroom will have a 10% chance of voiding items for machines running a "Needs Cleanroom" recipe.
-When at 100% efficiency, the cleanroom drains 4 EU/t. However, while it's charging up to that value (0% through 99%), the cleanroom will drain 40 EU/t. For this reason, it is recommended to have at least two amps of LV feeding into an LV energy hatch (or 1 amp of anything higher than LV feeding into an appropriate energy hatch).
+When at 100% efficiency, the cleanroom drains 4 EU/t. However, while it's charging up to that value (0% through 99%), the cleanroom will drain 40 EU/t. For this reason, it is recommended to have at least two amps of LV feeding into an LV energy hatch (or 1 amp of anything higher than LV feeding into an appropriate energy hatch).  Providing a higher tier Energy Hatch will [[overclock]] the cleanroom, making it gain efficiency faster at the cost of higher power use, even after 100% is achieved.
-== Machine Hulls ==
+=== Accessing the Cleanroom ===
+A Reinforced Door, Travel Anchor, and/or Elevator can all be used to enter and exit the cleanroom.  The door requires a redstone signal to open and must be closed for 100% efficiency.  Anchors and Elevators do not reduce a cleanroom's efficiency when used. The second Elevator block can be placed on top or below, while another Travel Anchor can be anywhere in its range.
-Machine hulls allow players to transfer items, fluids, and energy (henceforth abbreviated as IFE) in and out of the cleanroom. Putting IFE into a hull is easy enough. Treat it basically like any other inventory/tank when transferring items/fluids and treat it like a machine face when transferring power, since it can accept GT cables.
+=== Machine Hulls ===
-On the other side of the hull, rightclicking with a wrench will control where the "dot" face points and this face will be where IFE comes out. Note that the hull does '''not''' auto output items and fluids. There will need to be something pulling items and/or fluids out of the hull on the other side. Attaching GT conveyor and GT pump covers on a hull does not work because it itself holds no EU (it merely transports it) to power the covers. However, attaching GT pipes with covers attached to them (screwdriver set to "import") will work. The same goes for covers attached to machine faces (screwdriver set to "import") facing the machine hull dot face.
+Machine hulls allow players to transfer items, fluids, and energy in and out of the cleanroom. Putting ingredients into a hull is easy enough. Treat it basically like any other inventory/tank when transferring items/fluids and like a machine face when transferring power, since it can accept GT cables.
+On the other side of the hull, right-clicking with a Wrench will control where the "dot" face points and this face will be where ingredients come out. Note that the hull does '''not''' auto output items and fluids. There will need to be something pulling items and/or fluids out of the hull on the other side. Attaching a [[Conveyor]] and  [[Pump Cover]]s on a hull does not work because it itself holds no EU (it merely transports it) to power the covers. However, attaching [[Fluid Pipe]]s with covers attached to them (screwdriver set to "import") will work. The same goes for covers attached to machine faces (screwdriver set to "import") facing the machine hull dot face.
-EU is transferred directly to the cable or machine face the dot face is pointing at and does not need anything special "pulling" the EU out. A hull can only transfer as much energy as the tier of the hull. For example, an HV machine hull can only output an amp of HV.
+EU is transferred directly to the cable or machine face the dot face is pointing at and does not need anything special "pulling" the EU out. A hull can only transfer as much energy as the tier of the hull. For example, an HV Machine Hull can only output one Amp of HV.
-Because there is a max of 10 machine hulls (regardless of cleanroom size), it is important to be efficient with hulls. A single dedicated output hull from inside the cleanroom to the outside is highly recommended, rather than having an output hull for each machine inside. A dedicated power line is recommended as well.
+Because there are a max of ten machine hulls per multiblock, it is important to be efficient with hulls. A single dedicated output hull from inside the cleanroom to the outside is highly recommended, rather than having an output hull for each machine inside. A dedicated power line is recommended as well.
-== Sample Minimum Build ==
+== Sample Minimum Build ==
-The following is a sample Cleanroom build of minimal size (26 Plascrete, no Filter Casings) with automation to get you started with HV circuits. Note that this setup requires that you use the Reinforced Door to swap out the lens - remember to close the door when you're done.
+The following is a sample Cleanroom build of minimal size (26 Plascrete, no Filter Casings) with automation to get you started with HV [[Circuit]]s. Note that this setup requires using the Reinforced Door to swap out the lens - close the door promptly to preserve efficiency.
  Top Layer: