Open Computers

Requires learning Lua. Not inherently a transport system, but drones/robots can be upgraded to handle transporting items and fluids. Not sure on TPS/FPS implications for servers/clients with large setups, or for potential speed. Standing blocks can substitute for a redstone control system. Requires significant infrastructure before useful operations, including power. Can be used to automate assembly line and infusion, but that will require quite a bit of coding. Basically advanced, technology based golems you have to program yourself. Could be push or pull based on your level of programming ability? May be regarded as meta-automation, that is - a system to control and interface with AE and redstone based automation setups.